The Tampa Bay Buccaneers and Seattle Seahawks will meet in Week 5 of the NFL season. Tampa is looking to rebound from a tough loss at home this week, while the Seahawks aim to build on a dramatic last-second victory. Seattle enters as a favorite at home as they look for their fourth win in a row. Before this matchup between NFC teams with 3-1 records, you can find my Buccaneers vs Seahawks prediction below.
Our Buccaneers vs Seahawks Pick
- Pick: Seahawks −3.5
- Confidence: 3/5
Game Snapshot
- Matchup: Tampa Bay Buccaneers vs Seattle Seahawks
- Date & Time: Sunday, October 5, 2025, 4:05 PM ET
- Venue: Lumen Field, Seattle, WA
- Broadcast: CBS
Buccaneers vs Seahawks Odds
| Spread | Moneyline | Total |
|---|---|---|
| Seahawks −3.5 | Seahawks −185 / Bucs +155 | 44.5 points |
Key Storylines
- Tampa’s receiving corps: Mike Evans is out for multiple weeks with a hamstring injury, meaning Baker Mayfield will lean heavily on secondary options. Chris Godwin is coming off an injury and caught just three passes for 26 yards in Tampa’s loss to the Eagles in Week 4. Rookie Emeka Egbuka showcased big-play ability with 101 receiving yards and a touchdown against Philadelphia. He will try to pick up the slack again here.
- Seattle’s offense: Sam Darnold has settled in as the starting quarterback of the Seahawks. Kenneth Walker III and Zach Charbonnet have formed a nice one-two punch out of the backfield, while Jaxon Smith-Njigba has emerged as a top target through the air. The Seahawks are making the plays they need to make to win games on both sides of the ball.
- Home-field advantage & rest: The Seahawks will have some extra rest going into this game after their Thursday night win over Arizona. Tampa is traveling cross-country at a rest disadvantage to play at a notoriously difficult place to play in Lumen Field.
- Defensive Outlook: Seattle has not allowed more than 20 points in a game yet this season. They will try to keep that streak alive this week against Baker Mayfield and the Bucs.
Quarterback Play
Baker Mayfield has shown poise in close games so far this season. In Week 4, Mayfield attempted 40 passes for 289 yards, two touchdowns, and one interception. Seattle’s defense will aim to bring heat from all angles at Mayfield and the Bucs’ signal caller will try to avoid being impacted by a good defense on the road here.
Sam Darnold has played well thus far in his first season in Seattle. Darnold has completed 70% of his passes so far this year, with five touchdown passes and two interceptions. He is doing exactly what Seattle needs him to do to win games by avoiding turnovers and simply managing games effectively.
Betting Trends
- Tampa Bay is 2-2 against the spread so far this season.
- Seattle is 3-1 against the spread heading into Week 5.
- Both teams are 2-2 in their over/unders going into this game.
Buccaneers vs Seahawks Model Projection
Score Projection: Tampa Bay 20 – Seattle 24
Win Probability: Tampa Bay 38%, Seattle 62%
Final Thoughts
Seattle has a rest advantage and home-field advantage going into this game. The Bucs tend to play up or down to their level of competition and certainly won’t make this an easy game for the Seahawks. But I do recommend laying the points with Seattle, as they should get a fourth straight win at the expense of the road-weary Bucs.
