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Brooklyn Nets vs Indiana Pacers Prediction - 3/22/2025

Brooklyn Nets vs Indiana Pacers Prediction – 11/5/2025

Updated November 5, 2025 • 3 min read

The Brooklyn Nets will face the Indiana Pacers on Wednesday night in a game between two struggling Eastern Conference teams. These teams have one combined win between them, but the good news here is that one of these teams is required to win this game. Who will be the team that gets that win? I will attempt to answer that question below with my Nets vs Pacers prediction.

Our Nets vs Pacers Pick

  • Pick: Over 233.5
  • Confidence: ★★☆☆☆

Game Snapshot

  • Matchup: Brooklyn Nets @ Indiana Pacers
  • Date & Time: Wednesday, November 5, 2025, 7:00 PM ET
  • Venue: Gainbridge Fieldhouse, Indianapolis, Indiana
  • Broadcast: NBA League Pass

Key Storylines

Brooklyn remains winless and is desperately seeking relief from an 0‑7 start. Their offense has struggled, ranking near the bottom in points per game and shooting efficiency. Their defense has been the worst in the league by many metrics. But this game offers them a chance to get a win over a similarly struggling opponent.

Indiana hasn’t been much better than Brooklyn. Their 1‑6 record belies the fact that early‑season injuries and inconsistency have made it hard for them to play at the level they did during last year’s NBA Finals run. But they do have a win over the Golden State Warriors this season and are capable of playing well despite all of the injuries impacting them.

Pascal Siakam is leading the Pacers with 26.0 points, 8.4 rebounds and 5.3 assists per game. Brooklyn’s offensive burden falls heavily on Cam Thomas (24.4 PPG) and Michael Porter Jr. (20.8 PPG). But both teams have lacked consistent contributions from other players. The Nets are without Haywood Highsmith due to injury, while Indiana is without Andrew Nembhard, Bennedict Mathurin, and Tyrese Haliburton. None of those absences are helpful when a team is struggling as much as these teams are.

Head‑to‑Head & Betting Trends

  • This is the first of three games scheduled between these teams this season.
  • Indiana is 5-2 against the spread despite their poor record to start the year.
  • Brooklyn is 2-4-1 against the spread this season.
  • The Pacers have stayed under the total in five of their first seven games.
  • Brooklyn has gone over the total in five of its first seven outings.

Best Player Props to Watch

PlayerProp
Pascal SiakamOver 26.5 points
Cam ThomasOver 23.5 points
Isaiah JacksonOver 9.5 points

Nets vs Pacers Model Projection

Score Projection: Pacers 125 – Nets 118
Win Probability: Pacers 71%, Nets 29%

Final Thoughts

The Pacers should win this game at home to get a second victory on the season at the expense of the winless Nets. But I’m not sure I like the idea of backing either team to get a win right now with how bad they have played. Instead, I’m going to take the over in this matchup, as both defenses should continue to struggle against some good individual offensive talent.


Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: Brooklyn Nets, Indiana Pacers
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