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St. Louis Cardinals vs New York Mets Prediction - 4/20/2025

St. Louis Cardinals vs New York Mets Prediction, Preview & Parlay Picks – 6/9/2026

Updated June 9, 2026 • 4 min read

The St. Louis Cardinals open a three-game series against the New York Mets on Tuesday night at Citi Field with both clubs heading in different directions. St. Louis enters the contest at 35-28 and remains firmly in the National League playoff picture, while New York sits at 29-36 and is trying to climb back into the Wild Card race. The pitching matchup features Dustin May for the Cardinals against Freddy Peralta for the Mets, giving bettors an intriguing duel between two right-handers.

St. Louis has held a clear edge offensively, ranking ahead of New York in batting average, on-base percentage, slugging percentage, runs scored, and home runs. The Mets have countered with stronger pitching and slightly better run prevention. Tuesday’s opener will likely come down to whether the Cardinals can continue their consistent offensive production against Peralta and a Mets bullpen that has been one of the bright spots for New York this year.

Our Cardinals vs Mets Prediction

  • Pick: Cardinals Moneyline
  • Confidence: 3.5 out of 5

St. Louis Cardinals vs New York Mets Model Projection

  • Score Projection: Cardinals 5 – Mets 4
  • Win Probability: Cardinals 54%, Mets 46%

The market has installed New York as a slight favorite because of Peralta’s superior season ERA and home-field advantage. But the Cardinals have scored 278 runs compared to New York’s 265 while posting a .242 team batting average versus the Mets’ .230 mark. They have also shown more power and a better on-base percentage throughout the season.

May’s 4.59 ERA is not impressive, but he has generally kept the Cardinals competitive and benefits from stronger offensive support. Peralta has been effective with a 3.63 ERA, though New York’s offense ranks near the bottom of the league in several key categories. With the Cardinals owning the better lineup and entering with a stronger overall record, the value appears to be on the road underdog.

Game Snapshot

  • Matchup: St. Louis Cardinals vs New York Mets
  • Date & Time: Tuesday, June 9, 2026, 7:10 PM ET
  • Starting Pitchers: Dustin May vs Freddy Peralta
  • Stadium: Citi Field, Queens, NY
  • Broadcast: MLB.tv

St. Louis Cardinals vs New York Mets Same Game Parlay

  • Leg 1: Cardinals Moneyline +108
  • Leg 2: Over 8 Runs -102
  • Leg 3: Alec Burleson 2+ Total Bases +129

Parlay Odds: +465

The Cardinals have been the more productive offense all season, and their lineup has a favorable matchup against a Mets team that has struggled to generate consistent scoring support. The total of eight runs is modest, given the offensive edge held by St. Louis and May’s tendency to allow traffic on the bases. As a result, this three-leg Same Game Parlay could have legs in Queens on Tuesday night.

St. Louis Cardinals vs New York Mets Home Run Prop

Juan Soto to Hit a Home Run +323

Even during a disappointing season for the Mets, Soto remains their premier power threat. May has allowed five home runs in 66.2 innings, and Soto’s ability to drive the ball to all fields makes him the most appealing home run option in this matchup. If New York wins, there is a strong chance Soto plays a major role.

Betting Trends & H2H

  • The Cardinals are 2-1 against the Mets so far this season.
  • St. Louis enters the series with a 35-28 record.
  • The Mets enter the series with a 29-36 record.
  • St. Louis is 16-12 on the road this season.
  • New York is 15-15 at home this season.
  • The Cardinals are 27-32-4 in the over/under market this season, favoring the under.
  • The under is 32-28-5 in Mets games this year.

Stat Comparison

CategoryCardinalsMets
Batting Average.242.230
OPS.708.661
wOBA.315.294
wRC+10289
Team ERA4.093.75
xFIP4.183.88

The statistical comparison highlights the main handicap in this game. New York’s pitching metrics are respectable, but the offense continues to lag behind league average. St. Louis owns the stronger lineup, more consistent run production, and a significantly better overall record. While Peralta gives the Mets a chance to control the game early, the Cardinals have more paths to victory over nine innings. Backing St. Louis as an underdog offers value as a result.

More Baseball Betting Resources

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Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: New York Mets, St. Louis Cardinals
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