The New York Giants and Denver Broncos will meet in Week 7 of the NFL season on Sunday. The Giants are coming off their best performance of the season against the defending champion Philadelphia Eagles and are generating some hype around their young offensive nucleus. They will try to take that show on the road to defeat a Broncos team that is off to a very strong start of their own. Here, I break down this inter-conference matchup and make my Giants vs Broncos prediction for Sunday.
Our Giants vs Broncos Pick
- Pick: Broncos -7
- Confidence: 3 out of 5
Game Snapshot
- Matchup: New York Giants @ Denver Broncos
- Date & Time: Sunday, October 19, 2025, 4:05 p.m. ET
- Venue: Empower Field at Mile High, Denver, CO
- Broadcast: CBS
Giants vs Broncos Odds
| Spread | Moneyline | Total |
|---|---|---|
| Denver –7 | Broncos –425 | Giants +320 | Over/Under 40.5 |
Key Storylines
The Broncos’ defense has been a talking point all season, and for good reason. Denver leads the league in sacks, pressures, and pressure percentage. They are second in the league in points per game allowed. New York’s rookie quarterback Jaxson Dart will be under constant duress and could look a lot different than the player we saw lead his team to a win over the Eagles last week.
However, Denver’s offense has been inconsistent, especially in the passing game. The loss of left guard Ben Powers to a torn bicep is a major blow to their interior line play. That could invite pressure and disruption, especially against a defense that has played well in recent weeks.
On the Giants’ side, Dart has delivered on the ground as much as with his arm, and running back Cam Skattebo continues to be a spark plug. New York’s upset over the Eagles has ignited buzz about their upside, but there is a difference between winning at home and doing so in a hostile environment.
Quarterback Play
Bo Nix: Nix has been solid, entering this game with nine touchdown passes and four interceptions. He won’t be pressured to carry a big load but he must manage the game, avoid turnovers, and let his defense do the heavy lifting.
Jaxson Dart: Dart has perhaps been the most intriguing rookie quarterback to watch this season. In his recent outings, he’s delivered both in the air and on the ground. Against the Eagles, he completed 17-of-25 passes for 195 yards and one passing touchdown. He also added 58 rushing yards and a touchdown on the ground. But he struggled in his first road start against the Saints and will try to be better here.
Betting Trends
- The Giants are 3-3 against the spread this season.
- Denver is 2-3-1 against the spread going into Week 7.
- The Giants have had four of their first six games go under their totals.
- Denver has stayed under the total in five of their first six games.
Giants vs Broncos Model Projection
Score Projection: Giants 16 – Broncos 26
Win Probability: Giants 22%, Broncos 78%
Final Thoughts
Full disclosure: I am a New York Giants fan. There is nothing more I want to see than Jaxson Dart and Cam Skattebo celebrating another win after this game. But I just don’t think that is going to happen. The Broncos’ defense should make life very tough on Dart and I receommend laying the points with the Broncos in this one.
