The San Antonio Spurs and New Orleans Pelicans will meet in NBA action on Friday night. The Spurs earned one of the most impressive wins in the NBA this season to open their campaign. They will try to improve to 2-0 on the season by beating New Orleans. Before tip-off from the Crescent City, continue reading to get my Spurs vs Pelicans prediction in Western Conference action.
Our Spurs vs Pelicans Pick
- Pick: Spurs -4.5
- Confidence: ★★★★☆
Game Snapshot
- Matchup: San Antonio Spurs @ New Orleans Pelicans
- Date & Time: Friday, October 24, 2025, 8:00 PM ET
- Venue: Smoothie King Center, New Orleans, LA
- Broadcast: NBA League Pass
Key Storylines
The San Antonio Spurs enter this matchup with a surge of momentum following a dominant 125–92 victory over the Dallas Mavericks. Victor Wembanyama enjoyed a sensational return after missing the final three months of the previous season due to a blood clot. Wemby had 40 points and 15 rebounds in just 30 minutes of play. His performance has set high expectations for the Spurs’ season.
The New Orleans Pelicans are looking to rebound from a 128–122 loss to the Memphis Grizzlies in their opener. They squandered a 15-point lead to lose that contest. Starting center Yves Missi left the game with an ankle injury, adding injury to insult, rather than the other way around. The Pelicans will need to address their defensive issues to compete effectively against the Spurs.
This game will pit a pair of former number-one overall draft picks against one another. Wembanyama and Zion Williamson were both drafted to be the faces of their respective franchises. But Williamson has struggled to stay on the floor throughout his career and a game like this one is a chance for him to prove that he’s still an elite player.
Head-to-Head & Betting Trends
- The Pelicans won three of their four meetings against the Spurs last season.
- New Orleans failed to cover the spread in their first game of the season.
- San Antonio covered the spread convincingly in their win over the Mavs on Wednesday.
- New Orleans saw their season opener go over the total.
- The Spurs had their first game go under the total.
Best Player Props to Watch
| Player | Prop |
|---|---|
| Victor Wembanyama | Over 28.5 Points |
| Zion Williamson | Over 24.5 Points |
Spurs vs Pelicans Model Projection
Score Projection: Spurs 118 – Pelicans 110
Win Probability: Spurs 65%, Pelicans 35%
Final Thoughts
With Victor Wembanyama’s impressive return and the Spurs’ defensive improvements, they are well-positioned to secure a road victory against the Pelicans. The defense of the Pelicans struggled in key moments against the Grizzlies and we should see the Spurs win and cover the spread on the road in this matchup from Smoothie King Center.
