Los Angeles Lakers vs Charlotte Hornets Prediction – 11/10/2025

The Los Angeles Lakers and Charlotte Hornets will meet at Spectrum Center in Charlotte on Monday night. Los Angeles is off to a nice start to the season despite a long injured list and they will try to keep it going against a struggling Charlotte squad here. Before tip-off from Charlotte, continue reading to get my Lakers vs Hornets prediction for this matchup.

Our Lakers vs Hornets Pick

Pick: Lakers -7.5
Confidence: ★★★☆☆

Game Snapshot

• Matchup: Los Angeles Lakers @ Charlotte Hornets
• Date & Time: Monday, November 10, 2025, 7:00 PM ET
• Venue: Spectrum Center, Charlotte, North Carolina
• Broadcast: NBA League Pass

Key Storylines

• The Lakers enter at 7‑3 and have won four of their last five games. Their offense is clicking, though they did struggle in a road loss to the Atlanta Hawks in their last game.
• The Hornets are 3‑6 and have lost five of their last six games. Their defense has been particularly vulnerable, giving up 121 points per game.
• The Lakers are still managing some injury concerns: LeBron James is out (back/scatica), Gabe Vincent is out (ankle), and Austin Reaves is listed as questionable with a groin strain.
• On the Hornets’ side: LaMelo Ball, Grant Williams, and Josh Green are all out, while Miles Bridges is questionable.
• The Lakers are off to a strong start on the road this season. They are 4-1 away from Crypto.com Arena and will try to continue to have success on the road in this matchup.

Head‑to‑Head & Betting Trends

• The Lakers are 7‑3 against the spread this season.
• The Hornets are 4‑5 against the spread to begin the year.
• The Lakers have gone over the total in eight of their first 10 games.
• Charlotte has gone under the total in five of their nine outings.
• This is the first of two games the Lakers and Hornets will play against each other in the regular season.

Best Player Props to Watch

Lakers vs Hornets Model Projection

Score Projection: Los Angeles Lakers 124 – Charlotte Hornets 114
Win Probability: Lakers 74%, Hornets 26%

Final Thoughts

The strong start to the season for the Los Angeles Lakers should continue on Monday night in Charlotte. The Hornets are struggling defensively and that is not a recipe for success when taking on Luka Doncic. Look for Doncic to have another big game here and for the Lakers to improve to 5-1 on the road this season while covering the spread as a favorite over the Hornets.

Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.