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Cleveland Cavaliers vs Detroit Pistons Pick - 3/28/2025

Cleveland Cavaliers vs Detroit Pistons Prediction – 10/27/2025

Updated October 27, 2025 • 3 min read

The Cleveland Cavaliers and Detroit Pistons will meet on Monday night at Little Caesars Arena in Detroit. Both teams enter the game with identical 2-1 records, making this Central Division matchup important for early-season positioning in the standings. The Cavaliers are slight favorites, but both teams have won two games in a row and will look for a third straight here. Before tip-off, continue reading to get my Cavaliers vs Pistons prediction.

Our Cavaliers vs Pistons Pick

  • Pick: Pistons +2.5
  • Confidence: ★★★★☆

Game Snapshot

  • Matchup: Cleveland Cavaliers @ Detroit Pistons
  • Date & Time: Monday, October 27, 2025, 7:00 PM ET
  • Venue: Little Caesars Arena, Detroit, MI
  • Broadcast: Peacock

Key Storylines

  • Injuries: The Cavaliers are without All-Star point guard Darius Garland, who is recovering from offseason surgery on his left big toe. Sharpshooter Max Strus is also out for the Cavs early in the season. Pistons guard Jaden Ivey is sidelined for at least four weeks following arthroscopic knee surgery. Caris LeVert and Marcus Sasser are both questionable for Detroit.
  • Recent Form: The Cavaliers are coming off a 118-113 victory over the Milwaukee Bucks, with Evan Mobley scoring 23 points and going a perfect 12-for-12 from the free-throw line. Donovan Mitchell added 24 points, including 10 in the fourth quarter. The Pistons defeated the Boston Celtics 119-113, despite Jaylen Brown scoring 41 points in a losing effort for Boston. Both teams have won two games in a row and are looking to make a statement in this contest.
  • Star Matchup: This game features a fun matchup between stars. Cleveland’s Donovan Mitchell is off to a great start to this season. He is averaging 30 points per game through three games. Detroit’s Cade Cunningham is averaging 23 points per game and nine assists. He is sixth in the league in assists per game early in the year.

Head-to-Head & Betting Trends

  • Past Meetings: The Cavaliers have won 12 of their last 13 regular-season games against the Pistons.
  • ATS Records: The Cavaliers are 0-3 against the spread this season. The Pistons are 2-1 against the spread.
  • Over/Under Trends: Cleveland is 2-1 to the over so far this season. Detroit is 1-1-1 on over/unders early in the year.

Best Player Props to Watch

PlayerProp
Evan MobleyOver 8.5 rebounds
Donovan MitchellOver 27.5 points
Tobias HarrisUnder 1.5 three-pointers made

Cavaliers vs Pistons Model Projection

  • Score Projection: Cavaliers 116 – Pistons 117
  • Win Probability: Cavaliers 50%, Pistons 50%

Final Thoughts

This game is a toss-up for me, especially with the Cavs missing two starters on the road. The duo of Mitchell and Mobley are incredible, but the Pistons have the depth to keep up with them for the most part. I’ll take the points with the Pistons here, as we should see a close game no matter who ends up getting the win.


Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: Cleveland Cavaliers, Detroit Pistons
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