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Philadelphia 76ers vs Boston Celtics Prediction - 3/6/2025

Boston Celtics vs Philadelphia 76ers Prediction: Boston Holds Momentum Entering Game 4

Updated April 26, 2026 • 3 min read

Game 4 between the Boston Celtics and Philadelphia 76ers is set for Sunday, with the series leaning toward Boston after a 108-100 win in Game 3. The Celtics now hold a 2-1 edge, while Philadelphia faces growing pressure with injury concerns surrounding its top player. Boston is the favorite going into this game as well, and you can find my Celtics vs 76ers Game 4 prediction below.

Celtics vs 76ers Game 4 Pick

  • Pick: Boston Celtics -7.5
  • Confidence: 4 out of 5

Game Snapshot

  • Matchup: Boston Celtics @ Philadelphia 76ers
  • Date & Time: Sunday, April 26, 7:00 PM ET
  • Venue: Xfinity Mobile Arena, Philadelphia, Pennsylvania
  • Broadcast: NBC, Peacock

Key Storylines

Boston enters Game 4 with control of the series and a strong statistical profile. The Celtics posted a 56-26 regular season record and carry a +7.7 net rating, supported by efficient three-point shooting at 36.7% and a top-tier defense allowing just 107.2 points per 100 possessions. They battled back from an early deficit in Game 3 and pulled away late, as their superior depth was a factor in helping them retake the lead in this series.

The Philadelphia 76ers face a different situation. The 76ers are dealing with the likely absence of Joel Embiid, who remains sidelined while recovering from surgery. Without him, the team leans heavily on its perimeter creation, particularly from Tyrese Maxey, who has carried the scoring load. Despite a solid offensive nucleus without Embiid, not having someone who can get easy baskets in the painted area consistently is a problem.

Key Players

Philadelphia 76ers

  • Tyrese Maxey is the engine of the offense, averaging 28.3 points and 6.6 assists per game. He poured in 31 points in Game 3 and continues to handle a high usage rate.
  • Paul George adds scoring support and veteran presence, contributing 18 points in the last outing while helping space the floor.
  • Kelly Oubre Jr. has chipped in 17 points in the last game and provides athletic scoring on the wing, though his health remains a concern.

Boston Celtics

  • Jaylen Brown leads the team with 28.7 points per game, combining efficiency with strong perimeter defense. He scored 25 points to help the Celtics win Game 3.
  • Jayson Tatum contributes across the board and delivered 25 points in Game 3, including clutch late scoring.
  • Derrick White averages 16.5 points and 5.4 assists, serving as a stabilizing presence and strong two-way contributor. He was only 3/12 from the field in Game 3 and the Boston Celtics will need more from him here.

Head-to-Head & Betting Trends

  • Boston leads the current playoff series 2-1.
  • Boston is 4-3 against the Celtics between the regular season and playoffs.
  • The Celtics are 50-35 against the spread going into this contest.
  • The Sixers are 46-40 against the spread entering Game 4.

Celtics vs 76ers Game 4 Model Projection

  • Score Projection: Boston Celtics 116 – Philadelphia 76ers 106
  • Win Probability: Boston Celtics 67%, Philadelphia 76ers 33%

Boston holds clear advantages in depth, defense, and late-game execution, all of which have shown up consistently in this series. The absence of a dominant interior presence for Philadelphia places added pressure on Maxey and the perimeter group to carry the offense, which becomes difficult against a disciplined Celtics defense. I project a win of about 10 points for the Celtics, and for Boston to leave Philly with a 3-1 lead and a chance to close things out at home in Game 5.

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Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: Boston Celtics, Philadelphia 76ers
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