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Philadelphia 76ers vs Boston Celtics Prediction - 3/6/2025

Boston Celtics vs Philadelphia 76ers Prediction: Who Takes a 2-1 Lead In Game 3?

Updated April 23, 2026 • 3 min read

The Boston Celtics and Philadelphia 76ers will meet in Game 3 of their first-round playoff series on Friday night. Boston controlled the opener in dominant fashion, before Philadelphia answered with a decisive 111-97 win in Game 2 behind elite perimeter shooting. Now the series heads to Philadelphia for Game 3, where adjustments, health questions, and shooting regression will shape the outcome. Here, I break down Celtics vs 76ers Game 3 and bring you my best bet for the game.

Celtics vs 76ers Game 3 Pick

  • Pick: 76ers +7.5
  • Confidence: 4 out of 5

Game Snapshot

  • Matchup: Boston Celtics @ Philadelphia 76ers
  • Date & Time: Friday, April 23, 7:00 PM ET
  • Venue: Xfinity Mobile Arena, Philadelphia, Pennsylvania
  • Broadcast: Prime Video

Key Storylines

  • This series is tied 1-1 after Philadelphia’s Game 2 win.
  • Boston shot just 26% from three in Game 2 after dominating Game 1.
  • Philadelphia hit 19 threes at a 49% clip in the win in Game 2.
  • Joel Embiid is listed as questionable while recovering from surgery, and a return for the Philly big man would change this game dramatically.
  • Consistency will determine the outcome of this game, after both teams had one very good performance and one very bad performance in the first two games in Boston.

Key Players

Philadelphia 76ers

  • Tyrese Maxey: Averaging 28.3 points and 6.6 assists per game, Maxey drives the offense and thrives in high-usage playoff situations. He posted 29 points and 9 assists in Game 2 and continues to exploit defensive switches.
  • VJ Edgecombe: The rookie delivered 30 points and 10 rebounds in Game 2, showcasing scoring ability and energy on the glass. His perimeter shooting was a major factor in the upset.
  • Paul George: Added 19 points in Game 2 and provides veteran scoring and spacing. His consistency helps stabilize the offense without Embiid.

Boston Celtics

  • Jaylen Brown: Averaging 28.7 points per game, Brown led all scorers with 36 in Game 2. He remains Boston’s most reliable downhill scorer.
  • Jayson Tatum: Contributed 19 points and 14 rebounds in Game 2. His all-around production remains critical, especially if outside shooting struggles continue.
  • Derrick White: Averaging 5.4 assists per game, White’s playmaking and perimeter defense are key to controlling tempo and limiting Maxey.

Head-to-Head & Betting Trends

  • These teams are 3-3 against each other so far this season.
  • Boston is 50-34 against the spread this season, the best mark in the NBA between the regular season and playoffs.
  • Philadelphia enters this matchup at 45-40 against the spread for the year.

Celtics vs 76ers Game 3 Model Projection

  • Score Projection: Boston Celtics 115 – Philadelphia 76ers 111
  • Win Probability: Boston Celtics 64%, Philadelphia 76ers 36%

The biggest variable going into this game remains the status of Embiid. Even if he suits up, conditioning and minutes would likely be limited, making it difficult for him to shift the game completely. Without him at full strength, Philadelphia relies heavily on perimeter shot-making, which can be volatile. But I do think that the Sixers will keep this game close with or without Embiid, and I’ll take the points with the Sixers on Friday night.

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Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: Boston Celtics, Philadelphia 76ers
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