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San Diego Padres vs Los Angeles Dodgers Pick - 6/19/2025

San Diego Padres vs Los Angeles Dodgers Prediction & Preview – 7/2/2026

Updated July 2, 2026 • 4 min read

The Los Angeles Dodgers welcome the San Diego Padres to Dodger Stadium on Thursday night for the opener of a four-game series that carries plenty of weight in the National League West race. The Dodgers roll in at 56-31 and have a commanding lead in the division, while the Padres arrive at 43-42 having dropped 5 in a row, including a lopsided 23-3 defeat to the Cubs. Randy Vásquez takes the mound for San Diego against Roki Sasaki, and we will break down their matchup from LA below.

Our Padres vs Dodgers Prediction

  • Pick: Dodgers ML (-198)
  • Confidence: 3 out of 5

Padres vs Dodgers Model Projection

  • Score Projection: Padres 3 – Dodgers 6
  • Win Probability: Padres 34%, Dodgers 66%

San Diego’s offense has gone cold at the worst possible time, batting just .224 as a team with a .300 on-base percentage, and its pitching staff has slipped to a 4.16 ERA over the last stretch of games. Los Angeles, by comparison, ranks at or near the top of baseball in batting average, on-base percentage, and slugging, with Shohei Ohtani (18 home runs, 50 RBIs) leading a lineup that just scored 9 runs in two of their last three games against the Athletics. Vásquez has been the more consistent arm by record, but Sasaki gets the benefit of a red-hot supporting cast and a home ballpark where the Dodgers have been difficult to beat.

San Diego does have some individual pieces trending the right way, most notably Manny Machado (16 home runs, 46 RBIs) and Fernando Tatis Jr., who launched two homers in his last outing. But a five-game skid against a Dodgers club that just dismantled the Padres 15-3 earlier this week is a tough combination to bet against. Our projection favors Los Angeles to win comfortably while San Diego’s bats work to find their footing again.

Game Snapshot

  • Matchup: San Diego Padres vs Los Angeles Dodgers
  • Date & Time: Thursday, July 2, 2026, 10:10 p.m. ET
  • Starting Pitchers: Randy Vásquez (6-6, 4.44 ERA) vs Roki Sasaki (3-5, 4.88 ERA)
  • Stadium: UNIQLO Field at Dodger Stadium, Los Angeles, CA
  • Broadcast: MLB Network

Padres vs Dodgers Same Game Parlay

  • Dodgers Moneyline (-198)
  • Over 8.5 Total Runs (-121)
  • Shohei Ohtani Over 1.5 Total Bases (-114)

Combined odds for this parlay check in around +300. The logic here is straightforward: Los Angeles is heavily favored for good reason given its offensive advantage over San Diego, an 8.5 total lines up with a park and pair of starters (Sasaki’s 4.88 ERA, Vásquez’s 4.44 ERA) that have both struggled with the long ball this season, and Ohtani has feasted against right-handed pitching all year while sitting near a coin flip to clear 1.5 total bases even against strong arms.

Padres vs Dodgers Home Run Prop

Shohei Ohtani to hit a home run is the play at +206 on DraftKings Sportsbook. Ohtani has gone deep 18 times already this season and has cleared 1.5 total bases in the bulk of his recent starts, and he draws a Padres pitching staff that has allowed hard contact in bunches during their recent losing streak. Vásquez has been homer-prone at points this year, and Ohtani’s raw power combined with a favorable matchup makes him the top target on the board.

Betting Trends & H2H

  • Season series: Dodgers lead 4-2 through 6 meetings, including a 15-3 win on June 27.
  • Dodgers enter with 4 wins in their last 5 games, while the Padres have lost 5 straight.
  • The under is 46-41 in Dodgers games this season.
  • The under is 46-38-1 in games involving the Padres this year.

Stat Comparison

CategoryPadresDodgers
Batting Average.224.265
OPS.672.789
wOBA.297.345
wRC+90119
Team ERA4.193.48
xFIP4.253.80

The main area to note going into this game is just how big the gap is between these teams offensively. The Dodgers’ overall pitching advantage will be blunted somewhat by Sasaki getting the start here. But the Dodgers should still put up runs in bunches and cover the runline in this matchup from Dodger Stadium.

More Baseball Betting Resources

  • All Baseball Betting Picks
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Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: Los Angeles Dodgers, San Diego Padres
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