Los Angeles Dodgers vs St. Louis Cardinals Prediction: Cards Look For Sixth Straight Win

The Los Angeles Dodgers and St. Louis Cardinals continue their weekend series on Saturday night after the Cardinals won the opener on Friday. Los Angeles enters at 20-12 but has dropped three straight games, including a 7-2 loss in the opener of this series. St. Louis, now 19-13, has surged with five consecutive wins and looks confident at home. Here, I break down this nationally televised matchup and make my Dodgers vs Cardinals prediction.

Dodgers vs Cardinals Pick

• Pick: Cardinals Moneyline
• Confidence: 3 out of 5

Game Snapshot

• Matchup: Los Angeles Dodgers vs St. Louis Cardinals
• Date & Time: Saturday, May 2, 2026, 7:15 PM ET
• Starting Pitchers: Roki Sasaki vs Michael McGreevy
• Stadium: Busch Stadium, St. Louis, MO
• Broadcast: FOX

Key Storylines

• The St. Louis Cardinals enter on a five-game winning streak, while the Dodgers have lost three in a row.
• Los Angeles’ offense has scored only five runs over its last three games.
• St. Louis dominated the series opener with 12 hits and strong bullpen work.
• The Dodgers remain betting favorites despite their recent struggles, while the Cardinals look to extend their winning streak to six straight games.
• The Cardinals have fought to within one game of first place in the NL Central standings and could move into a tie with a win today, while the Dodgers are a half-game up in the NL West standings.

Pitching Matchup

• Roki Sasaki carries a 6.35 ERA with 13 walks in 22.2 innings of work for the Los Angeles Dodgers.
• Michael McGreevy owns a 2.97 ERA and a 0.90 WHIP through 33.1 innings pitched.
• McGreevy has allowed three runs in 17 home innings this season and five home runs overall.
• Sasaki has allowed 7 home runs already and has struggled with command.

Key Players

• Shohei Ohtani is hitting a disappointing .261 and went hitless in the series opener.
• Jordan Walker is coming off a four-hit performance and is batting above .300 for the Cardinals.
• Nolan Gorman and Alec Burleson both homered in Friday’s win for St. Louis.

Recent Team Streaks

• The Dodgers are 2-3 in their last five games and have lost three straight games.
• The Cardinals are 5-0 in their last five games.

Betting Trends & H2H

• The Cardinals are 1-0 against the Dodgers so far this season.
• The under is 17-15 in Dodgers games so far this season.
• The over is 18-13 in games featuring the Cardinals in 2026.

Dodgers vs Cardinals Model Projection

• Score Projection: Dodgers 3 – Cardinals 5
• Win Probability: Dodgers 47%, Cardinals 53%

The numbers point to a tight game on Saturday night. While Los Angeles remains one of the top offensive teams in baseball with a .271 batting average and strong slugging metrics, their recent performance tells a different story. The Dodgers have struggled to convert scoring chances, and their current slump is backed by declining situational hitting. I’ll take the Cardinals to beat the Dodgers as an underdog for the second night in a row, as they should use their starting pitching advantage to take the lead and not look back.

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Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

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