The Alabama Crimson Tide (6-1, 4-0 SEC) will travel to Columbia to face the South Carolina Gamecocks (3-4, 1-4 SEC) on Saturday. The Crimson Tide are looking to extend their six-game winning streak, while South Carolina aims to rebound from recent struggles. Here, I break down this matchup in the SEC and give you my Alabama vs South Carolina prediction.
Our Alabama vs South Carolina Pick
- Pick: South Carolina +11.5
- Confidence: ★★★★☆
Game Snapshot
- Matchup: Alabama Crimson Tide vs South Carolina Gamecocks
- Date & Time: Saturday, October 25, 2025, 3:30 p.m. ET
- Venue: Williams-Brice Stadium, Columbia, SC
- Broadcast: ABC
Key Storylines
- Alabama’s Offensive Efficiency: Quarterback Ty Simpson has been exceptional this season, throwing for 1,931 yards and 18 touchdowns with only one interception. His performance has been instrumental in Alabama’s offensive success and he could be a Heisman Trophy contender if he keeps this up.
- South Carolina’s Offensive Struggles: The Gamecocks have struggled offensively, ranking among the worst in the SEC in scoring and rushing yards. Quarterback LaNorris Sellers has thrown for 1,134 yards, but the offense has been inconsistent overall for South Carolina.
- Injuries Impacting Alabama: Alabama has several key players listed on the injury report, including wide receiver Lotzeir Brooks (doubtful), right guard Geno VanDeMark (questionable), and tight end Danny Lewis (out). Despite these injuries, the Crimson Tide’s depth and talent should be enough to get them through this game with a win.
- SEC Implications: Alabama already controls its own destiny in the race to get to the SEC Championship Game. The Crimson Tide and Texas A&M are the only two teams without a loss in conference play this year. As long as Alabama keeps winning, they will make it to Atlanta.
Betting Trends & H2H
- Alabama: The Crimson Tide are 5-1-1 against the spread this season. Alabama is 4-3 to the over for the year.
- South Carolina: South Carolina is 3-4 against the spread this season and 0-2 against the spread in their last two games. The Gamecocks have gone under the total in five of their seven games.
- Head-to-Head: Alabama has dominated the recent series, winning the last five matchups by an average margin of 20 points.
Alabama vs South Carolina Model Projection
Score Projection: Alabama 31 – South Carolina 21
Win Probability: Alabama 82%, South Carolina 18%
Final Thoughts
There is no question that Alabama is the better team going into this game. But I think that the South Carolina Gamecocks will do enough to cover the spread in this contest. The Tide have played some tight games on the road early in the year and that should continue here against an SEC opponent. I’ll take the points with South Carolina in this game from Columbia.
