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Milwaukee Brewers vs Chicago Cubs Prediction - 6/19/2025

Milwaukee Brewers vs Chicago Cubs Prediction: First Place Up For Grabs In the NL Central

Updated May 20, 2026 • 4 min read

The Milwaukee Brewers and Chicago Cubs wrap up their midweek NL Central set on Wednesday night at Wrigley Field, and the division race is a huge storyline coming into this contest. Milwaukee has surged into form with 10 wins in its last 12 games, including a 5-2 victory over Chicago on Tuesday. The Cubs remain one of the league’s strongest home teams, though their lineup has cooled off in this series so far. With Kyle Harrison taking the mound for Milwaukee against Edward Cabrera for Chicago, this Brewers vs Cubs game could be a tight, low-scoring contest with first place in the NL Central on the line.

Our Brewers vs Cubs Pick

  • Pick: Milwaukee Brewers moneyline
  • Confidence: 3.5 out of 5

Game Snapshot

  • Matchup: Milwaukee Brewers vs Chicago Cubs
  • Date & Time: Wednesday, May 20, 2026, 7:40 PM ET
  • Starting Pitchers: Kyle Harrison vs Edward Cabrera
  • Stadium: Wrigley Field, Chicago, IL
  • Broadcast: MLB.tv

Key Storylines

  • Milwaukee has won 10 of its last 12 games and has climbed into the top spot in the NL Central race.
  • The Cubs entered this series with one of MLB’s best home records, but they have dropped the first two games of this series to fall behind the Brewers by a half game in the NL Central.
  • Brewers pitching has been dominant lately, holding the Cubs to 2.5 runs per game in this series.
  • Chicago’s offense struck out 13 times Tuesday and struggled to generate traffic on the bases until the eighth inning.
  • The winner of this game would go into Thursday with no worse than a tie for first place in the division standings, making this a huge game on both sides.

Pitching Matchup

Kyle Harrison has quietly become one of Milwaukee’s steadiest arms. The left-hander enters Wednesday with a 4-1 record and a 2.09 ERA while limiting damage with solid command and swing-and-miss stuff. Milwaukee has gone 6-2 on the runline in Harrison’s starts, and his ability to neutralize left-handed hitters could matter against a Cubs lineup that leans heavily on on-base production from the left side.

Edward Cabrera brings electric velocity for Chicago, though his outings can shift quickly because of control issues. Cabrera owns a 3-1 record with a 4.06 ERA and 45 strikeouts in 51 innings. His strikeout numbers remain strong, but walks and elevated pitch counts have shortened several outings. Milwaukee’s patient lineup could force him into stressful innings early.

The bullpen edge slightly favors Milwaukee entering this game. Brewers relievers have handled high-leverage spots effectively during the club’s recent run, while Chicago’s relief group has been less steady over the last week.

Key Players

  • Brice Turang, Brewers: Batting .292 with 7 home runs and 29 RBI. He went 3-for-4 with a homer Tuesday.
  • Jake Bauers, Brewers: Carrying a strong .292 average with 7 home runs and an active on-base streak.
  • Pete Crow-Armstrong, Cubs: Delivered late offense Tuesday and remains one of Chicago’s spark plugs.
  • Ian Happ, Cubs: Needs a bounce-back effort after a quiet first two games in the series.
  • Nico Hoerner, Cubs: Recorded 2 hits Tuesday and continues to set the tone near the top of the lineup.

Betting Trends & H2H

  • The Brewers are 2-0 against the Cubs so far this season.
  • The over/under is 1-1 in games between these division rivals this year.
  • Milwaukee is 13-9 on the road in 2026.
  • Chicago is 18-7 at home so far this year.

Brewers vs Cubs Model Projection

  • Score Projection: Milwaukee Brewers 4 – Chicago Cubs 3
  • Win Probability: Milwaukee Brewers 54%, Chicago Cubs 46%

Milwaukee enters this game playing sharper baseball in nearly every area. The Brewers are getting timely hitting, stronger bullpen work, and elite starting pitching during this recent stretch. Harrison’s current form also gives Milwaukee a favorable setup against a Cubs lineup that looked uncomfortable against quality velocity and breaking pitches Tuesday night. As a result, I’m taking the visitors to get a win in this spot and to complete a three-game sweep of Chicago.

More Baseball Betting Resources

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Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: Chicago Cubs, Milwaukee Brewers
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