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San Francisco Giants vs Los Angeles Dodgers Pick - 6/15/2025

San Francisco Giants vs Los Angeles Dodgers Prediction: Ohtani Pitching, Looking to Snap LA Losing Streak

Updated May 13, 2026 • 4 min read

An NL West rivalry continues Wednesday night at Dodger Stadium as the San Francisco Giants try to keep their recent surge going against a Los Angeles Dodgers club searching for answers. San Francisco has already taken control of the series after a 6-2 win on Tuesday, their fourth victory in five meetings against Los Angeles this season. With Shohei Ohtani on the mound for the Dodgers on Wednesday, Los Angeles will try to right the ship in this Giants vs Dodgers matchup.

Our Giants vs Dodgers Prediction

  • Pick: Giants +1.5
  • Confidence: 4 out of 5

Game Snapshot

  • Matchup: San Francisco Giants vs Los Angeles Dodgers
  • Date & Time: Wednesday, May 13, 2026, 10:10 PM ET
  • Starting Pitchers: Robbie Ray vs Shohei Ohtani
  • Stadium: Dodger Stadium, Los Angeles, CA
  • Broadcast: MLB.TV

Key Storylines

  • The San Francisco Giants have won 4 of 5 meetings against the Dodgers this season going into this game, including the first two games of this four-game series.
  • Los Angeles enters the game on a four-game losing streak and has dropped a half-game behind the San Francisco Giants in the NL West standings.
  • Shohei Ohtani is expected to pitch for LA, but may have reduced hitting responsibilities in this game. Given how much he has struggled at the plate this season, that might not be a bad thing.
  • The Dodgers have scored 3 runs or fewer in 10 of their last 13 games and need to step up offensively if they want to turn things around.

Pitching Matchup

Robbie Ray has quietly delivered a strong opening stretch for San Francisco. The veteran left-hander enters with a 3-4 record and a 2.76 ERA across 45.2 innings. His strikeout numbers remain excellent with 47 punchouts, and hitters are struggling to barrel his fastball when he gets ahead in the count. The Giants have not given him much support on the road, though Ray himself has continued to work deep into games.

Ohtani has looked nearly untouchable on the mound this season. Through 37 innings, he owns a 0.97 ERA with 42 strikeouts and an elite 0.81 WHIP. Opposing hitters have struggled badly against his splitter, and his command has improved with every outing. Even so, there is concern surrounding his workload after Los Angeles hinted that he may not hit while pitching this week. That could weaken the Los Angeles Dodgers lineup against a quality left-handed starter.

Key Players

  • Eric Haase hit 2 home runs Tuesday night and has provided unexpected power for San Francisco.
  • Jung Hoo Lee collected a key 2-run double in the latest win over Los Angeles.
  • Luis Arraez is batting .303 and continues to set the table for the Giants offense.
  • Shohei Ohtani snapped a 12-game homer drought Tuesday with a solo shot. He is also set to pitch in this game.
  • Andy Pages has been one of the Dodgers’ most productive hitters with a .318 average and 35 RBI.

Betting Trends & H2H

  • The Giants are 4-1 against the Dodgers so far this season.
  • LA has lost four games in a row coming into this matchup.
  • The Dodgers are 13-10 at home this season.
  • The Giants are 8-12 on the road on the year.

Giants vs Dodgers Model Projection

  • Score Projection: San Francisco Giants 3 – Los Angeles Dodgers 4
  • Win Probability: San Francisco Giants 46%, Los Angeles Dodgers 54%

This game has the feel of a playoff-style pitching duel. Ray has rediscovered his form, while Ohtani has produced ace-level numbers every time he has taken the mound. The Dodgers remain dangerous because of their lineup depth, though their recent offensive production has fallen sharply. With Ohtani possibly limited as a hitter and the Giants carrying confidence into this matchup, scoring opportunities may be limited. I’ll take the Giants to cover the runline, in a game that could go either way despite Ohtani’s presence on the mound.

More Baseball Betting Resources

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Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: Los Angeles Dodgers, San Francisco Giants
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