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Minnesota Timberwolves vs Denver Nuggets Pick - 4/1/2025

Minnesota Timberwolves vs Denver Nuggets Prediction: Denver Hopes to Stay Alive In Game 5

Updated April 27, 2026 • 4 min read

The Minnesota Timberwolves and Denver Nuggets will face off in Game 5 of their Western Conference first-round playoff series on Monday night. Minnesota holds a 3-1 edge after a dominant 112-96 win in Game 4, yet that victory came at a steep cost. Injuries to key contributors have shifted the outlook dramatically heading into Monday night in Denver. The Nuggets now face elimination on their home floor, while the Timberwolves must prove they can finish the job without key scoring options. Before tip-off in Denver, continue reading to get my Timberwolves vs Nuggets Game 5 prediction.

Timberwolves vs Nuggets Game 5 Pick

  • Pick: Denver Nuggets -10.5
  • Confidence: 3 out of 5

Game Snapshot

  • Matchup: Minnesota Timberwolves @ Denver Nuggets
  • Date & Time: Monday, April 27, 10:30 PM ET
  • Venue: Ball Arena, Denver, Colorado
  • Broadcast: NBC, Peacock

Key Storylines

The Minnesota Timberwolves enter Game 5 with control of the series but major uncertainty surrounding its roster. Anthony Edwards, who averaged 28.8 points per game during the regular season, is dealing with a knee injury and is expected to miss time. Donte DiVincenzo is already out for the season with a torn Achilles. Despite those setbacks, the Timberwolves delivered one of their most impressive performances in Game 4, fueled by a stunning 43-point outing from Ayo Dosunmu.

Denver is in a must-win situation to keep its season alive in Game 5. The Nuggets have struggled to generate consistent offense against Minnesota’s defense, scoring under 100 points in multiple games this series. Nikola Jokic continues to produce across the stat sheet, but efficiency has been an issue, and frustration for him boiled over late in Game 4. Playing at home gives Denver a clear edge, and history shows they are capable of responding in elimination scenarios.

Key Players

Denver Nuggets

  • Nikola Jokic: Averaging 27.7 points, 12.9 rebounds, and 10.7 assists, Jokic remains the engine of the offense for the Denver Nuggets. His ability to control the flow of Denver’s offense and create opportunities for himself and others is critical in an elimination game.
  • Jamal Murray: Coming off a 30-point effort in Game 4, Murray’s scoring is essential, especially with Minnesota focusing defensive attention on Jokic.

Minnesota Timberwolves

  • Ayo Dosunmu: Coming off a 43-point breakout performance, Dosunmu has emerged as a key scoring option with injuries piling up.
  • Rudy Gobert: Averaging 11.5 rebounds per game, Gobert’s rim protection and interior defense have limited Denver’s efficiency.

Head-to-Head & Betting Trends

  • Recent meetings: Minnesota has won 3 of the 4 games this series, including a 112-96 victory in Game 4. These teams are 4-4 against each other between the regular season and playoffs.
  • Denver ATS record: 45-41
  • Minnesota ATS record: 39-47

Timberwolves vs Nuggets Game 5 Model Projection

  • Score Projection: Minnesota Timberwolves 105 – Denver Nuggets 120
  • Win Probability: Minnesota Timberwolves 32%, Denver Nuggets 68%

Even with Minnesota holding a 3-1 series lead, the injuries to Edwards and DiVincenzo shift the outlook of this series significantly. The Timberwolves showed their depth in Game 4, but sustaining that level of production on the road against a desperate team is a tall order. Denver’s offensive ceiling remains higher, especially at home, and Jokic is unlikely to have another inefficient outing of that magnitude.

Expect the Nuggets to come out with urgency and control the game early. While Minnesota’s defense has been effective, the lack of its primary scorer creates limitations in late-game situations. I’m going to lay the points with the Nuggets here, as they should keep their season alive before heading back to Minnesota for Game 6.

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Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: Denver Nuggets, Minnesota Timberwolves
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