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san antonio spurs vs portland trail blazers prediction and preview

San Antonio Spurs vs Portland Trail Blazers Prediction: Wemby Questionable For Game 4

Updated April 25, 2026 • 4 min read

The first-round series between the San Antonio Spurs and Portland Trail Blazers has already delivered momentum swings, and Game 4 on Sunday could have more of the same. San Antonio enters with a 2-1 series lead after a convincing 120-108 comeback win in Game 3, fueled by its young core stepping up in a high-pressure spot. Portland still has home-court advantage and will try to bounce back in Spurs vs Trail Blazers Game 4 to even this series at two games apiece.

Spurs vs Trail Blazers Game 4 Pick

  • Pick: Spurs -5.5
  • Confidence: 4 out of 5

Game Snapshot

  • Matchup: San Antonio Spurs @ Portland Trail Blazers
  • Date & Time: Sunday, April 26, 3:30 PM ET
  • Venue: Moda Center, Portland, Oregon
  • Broadcast: ESPN

Key Storylines

The San Antonio Spurs seized control of the series with a dominant second half in Game 3, overcoming a 15-point deficit and showcasing their depth. The Spurs have now won two of the first three games and continue to generate efficient offense, averaging nearly 120 points per game this season. Their ability to respond without the concussed Victor Wembanyama remains the defining storyline entering Game 4, with Wemby questionable for this contest.

Portland must regroup after a collapse that exposed defensive issues and inconsistency late in games. The Trail Blazers have shown they can compete, including an impressive Game 2 win, but sustaining that level for four quarters has been a problem. Playing at home again gives them an opportunity to even the series, though the pressure is mounting for Portland.

Another key factor is the uncertain status of Wembanyama, who remains in concussion protocol. His absence has forced others into larger roles, and so far, the response has been impressive. Whether he returns or not, the Spurs have proven they can generate offense from multiple sources.

Key Players

Portland Trail Blazers

  • Scoot Henderson leads the Portland Trail Blazers with 23.3 points per game in the playoffs and drives the offense with his pace and scoring ability.
  • Jrue Holiday is coming off a 29-point performance in Game 3 and provides veteran leadership along with strong perimeter defense.
  • Donovan Clingan anchors the interior with 9.3 rebounds per game, giving Portland second-chance opportunities and rim protection.
  • Deni Avdija has been a primary scoring option during the season, averaging over 24 points per game, though he was limited in Game 3 after a huge start to his postseason.

San Antonio Spurs

  • Stephon Castle has emerged as a breakout playoff performer, averaging 22.7 points per game and scoring 33 in Game 3.
  • Dylan Harper delivered a standout 27-point, 10-rebound effort in Game 3, providing a major boost off the bench.
  • De’Aaron Fox contributes 18.6 points and 6.2 assists per game, giving San Antonio steady playmaking and scoring.
  • Luke Kornet has been a key presence on the glass, averaging 8.3 rebounds per game in the series and helping fill the rebounding void left by the injured Wembanyama.

Head-to-Head & Betting Trends

  • San Antonio leads the series 2-1 and is 4-2 against the Trail Blazers between the regular season and playoffs.
  • The Spurs are 48-36-2 against the spread this season.
  • Portland is 46-40 against the spread going into this game.

Spurs vs Trail Blazers Game 4 Model Projection

  • Score Projection: Spurs 118 – Trail Blazers 112
  • Win Probability: Spurs 64%, Trail Blazers 36%

San Antonio enters Game 4 as the more stable and efficient team. Even without its top scorer, the Spurs have demonstrated depth, ball movement, and the ability to close games strongly. The Spurs looked like they were on the ropes in Game 3, but their comeback and subsequent double-digit win is a clear sign that they can overcome adversity. I’ll lay the points with the Spurs here, as I expect them to cover the number and take a 3-1 series lead.

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Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: Portland Trail Blazers, San Antonio Spurs
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