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miami vs purdue prediction and preview

Miami Hurricanes vs Purdue Boilermakers Prediction: NCAA Tournament Second Round

Updated March 21, 2026 • 3 min read

The second round of the NCAA Tournament will resume on Sunday with a matchup between a high-powered Purdue squad and a confident Miami team that just turned in one of the more impressive opening-round wins. With a trip to the Sweet 16 on the line, the Boilermakers are favored to win this Miami vs Purdue matchup, while Miami will try to pull off an upset to reach the second weekend.

Game Snapshot

  • Matchup: Miami Hurricanes vs Purdue Boilermakers
  • Date & Time: Sunday, March 22, 12:10 PM ET
  • Venue: Enterprise Center, St. Louis, Missouri
  • Broadcast: CBS

Key Storylines

Purdue enters this game after a dominant 104-71 victory in the opening round, showing off its elite offensive ceiling. The Boilermakers have been one of the most efficient teams in the country all season, powered by strong guard play and perimeter shooting. Their ability to control tempo and create high-quality looks makes them a tough matchup for any opponent.

Miami, meanwhile, advanced with an 80-66 win over Missouri, fueled by strong rebounding and interior scoring. The Hurricanes controlled the glass and capitalized on second-chance opportunities, which will again be critical against a bigger Purdue front line. Miami has shown it can rise to the occasion, but consistency against top-tier competition has been mixed.

Key Players

Purdue Boilermakers

  • Braden Smith: The engine of the offense and one of the nation’s assist leaders. He is coming off a 26-point, 8-assist performance and consistently controls pace while creating open looks.
  • Fletcher Loyer: A reliable perimeter scorer who stretches defenses with his shooting ability. His spacing is key to Purdue’s offensive flow.

Miami Hurricanes

  • Malik Reneau: Dominant inside presence who scored 24 points in the first round. His ability to score in the paint and rebound will be central to Miami’s chances.
  • Tre Donaldson: Contributed 17 points in the opener and provides shot creation and perimeter scoring.
  • Shelton Henderson: Added 15 points last game and gives Miami another scoring option to balance the offense.

Stat Comparison

StatMiamiPurdue
Points per game81.982.3
Points allowed per game71.070.2
Field Goal %50%50%
Rebounds per game37.635.6
Assists per game16.220.0

Betting Trends

  • Purdue is 16-20 against the spread going into this game.
  • Miami is 18-14-1 against the spread this season.
  • The over is 19-17 in Purdue games this year.
  • Miami is 20-12-1 to the over entering this contest.

Miami vs Purdue Pick & Model Projection

  • Score Projection: Miami 71 – Purdue 80 ATS PRO
  • Pick: Purdue -7.5 ATS PRO
  • Confidence: 4 out of 5 ATS PRO
  • Win Probability: Miami 32%, Purdue 68% ATS PRO

Purdue’s offensive efficiency and depth give it a clear edge in this matchup. The Boilermakers excel in ball movement and shot selection, which should allow them to break down Miami’s defense over the course of the game. While Miami has shown it can compete physically and control the boards, sustaining that effort against a team with Purdue’s spacing and guard play is a difficult task. I recommend laying the points with the Boilermakers, as favorites continue to roll in the second round of this tournament.

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Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: Miami Hurricanes, Purdue Boilermakers
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