Virginia Cavaliers vs Missouri Tigers Gator Bowl Prediction – 12/27/2025

The 2025 TaxSlayer Gator Bowl will feature the Virginia Cavaliers (10-3) and Missouri Tigers (8-4) on Saturday in Jacksonville. This is a matchup between power conference teams that will be looking to end their seasons on a high note. Before they start playing for the final time in 2025, you can continue reading to find my Virginia vs Missouri prediction.

Our Virginia vs Missouri Pick

Game Snapshot

• Matchup: Virginia Cavaliers vs Missouri Tigers
• Date & Time: Saturday, December 27, 2025, 7:30 p.m.
• Venue: EverBank Stadium, Jacksonville, Florida
• Broadcast: ABC

Key Storylines

Virginia wrapped up an impressive ACC campaign with a 10-3 record, tying its single-season win mark last achieved in 1989 and arriving in the Gator Bowl with plenty of positives to look back on despite a loss to Duke in the ACC Championship Game. A victory would give the Cavaliers their first postseason bowl win since 2018 and an unprecedented 11-win season in program history.

Missouri endured an up-and-down season in the SEC, finishing 8-4 while capably navigating a tough schedule. Mizzou enters this game as a favorite, though the absence of starting quarterback Beau Pribula and several key receivers due to the transfer portal will make it harder for them to enjoy any offensive continuity. Freshman quarterback Matt Zollers is expected to start for the Tigers, placing extra responsibility on the rushing attack and the defense’s ability to control field position.

Quarterback Play

Virginia’s Chandler Morris offers experience while leading the Cavaliers’ offense. Morris has thrown for 2,802 yards with 16 touchdowns and nine interceptions on the season while contributing 245 rushing yards and five scores. He does not appear to be opting out of this game, which is good news for the Cavaliers.

Missouri’s offense has been led by Zollers in the absence of Pribula. Zollers’ limited experience includes a loss to Texas A&M and a win over Mississippi State. Zollers has completed about 53% of his passes for 402 yards with four touchdowns and one interception. Given the uncertainty at the position, Missouri’s offensive plan may lean heavily on its ground game and conservative play calling to mitigate turnovers.

Betting Trends & H2H

• Missouri is 1-0 all-time against Virginia, though that game came in 1973.
• Virginia is 8-5 against the spread so far this season.
• Missouri is 6-5-1 against the spread going into the Gator Bowl.
• The Cavaliers went 4-8-1 in the over/under market this season.
• The Tigers went over the total in 7 of their 12 games.

Virginia vs Missouri Model Projection

Final Thoughts

Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.