Philadelphia 76ers vs Chicago Bulls Prediction & ATS Pick – 12/26/2025

The Philadelphia 76ers enter Friday night looking to steady themselves against a Chicago Bulls team that has shown improved form over the past week. Philly will look to bounce back from an embarrassing home loss to the Brooklyn Nets, while the Bulls are shooting for their fifth win in a row. Here, I take a closer look at this contest from United Center and you can find my 76ers vs Bulls prediction below.

Our 76ers vs Bulls Pick

Game Snapshot

• Matchup: Philadelphia 76ers @ Chicago Bulls
• Date & Time: Friday, December 26, 2025, 7:30 PM ET
• Venue: United Center, Chicago, IL
• Broadcast: Prime Video

Key Storylines

Chicago comes into this contest having won four straight games while improving its defensive efficiency at home. The Bulls have benefited from improved ball movement, with Josh Giddey consistently creating scoring chances for teammates and pushing the tempo. Coby White continues to serve as a reliable perimeter option, giving Chicago spacing that has opened lanes for drives and kick-outs.

Philadelphia has navigated an inconsistent stretch driven in part by injury uncertainty. Joel Embiid and several rotation players have are listed as questionable going into this game, which places additional pressure on Tyrese Maxey to lead the offense. Maxey has answered the call, averaging 31 points per game while maintaining efficiency from deep. Philadelphia’s road record has remained respectable at 7-4, and the team has covered spreads consistently away from home. But the potential for more time off the floor for Embiid could be a problem.

This is an important game for both of these teams. The Sixers enter the night in fifth place in the Eastern Conference standings and the Bulls occupy 10th place. Both teams have their sights set on moving up in the East standings and wins in games like this one would be incredibly helpful in achieving that goal.

Head-to-Head & Betting Trends

• The Bulls defeated the 76ers 113-111 in their first matchup earlier this season.
• Philly is 17-11 against the spread this season.
• Chicago is 15-14 against the spread for the season.
• The Bulls have gone over the total in 15 of their 29 games this year.
• Philadelphia is 14-14 in the over/under market this season.

Best Player Props to Watch

76ers vs Bulls Model Projection

Final Thoughts

Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.