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seattle seahawks vs los angeles rams prediction and preview

Seattle Seahawks vs Los Angeles Rams Prediction – 11/16/2025

Updated November 16, 2025 • 3 min read

The Seattle Seahawks and Los Angeles Rams will do battle in an NFC West matchup this Sunday afternoon in one of the most compelling NFL games of the week. Both teams head into this contest with identical 7‑2 records, led by quarterbacks who are in the thick of the NFL MVP race. First place in the division will belong to the winner of this game and you can find my Seahawks vs Rams prediction right here.

Our Seahawks vs Rams Pick

Pick: Over 48.5
Confidence: ★★★★☆

Game Snapshot

  • Matchup: Seattle Seahawks vs Los Angeles Rams
  • Date & Time: Sunday, November 16, 2025, 4:05 PM ET
  • Venue: SoFi Stadium, Inglewood, California
  • Broadcast: FOX

Key Storylines

This is a heavyweight NFC West collision. Both teams sit at 7‑2 and are battling for not just division supremacy but potential home‑field advantage in the playoffs. The Rams have one of the league’s top scoring defenses and are playing with high confidence. But the Seahawks arrive on a roll, having just thumped Arizona 44‑22 for their fourth win in a row.

Playing on the road, Seattle has won each of its first four games outside of the Pacific Northwest this season. Los Angeles is 3-1 at home so far this season. But only one team can continue its run of dominance in this situation. And with the winner of this game moving into sole possession of first place in the NFC West, the stakes could not be higher.

Quarterback Play

Seattle’s Sam Darnold has thrown for 2,262 yards over 9 games, with 17 touchdown passes and 6 interceptions. His yards‑per‑attempt average is around 9.9, which puts him among the more efficient passers in the NFL this season. He’s also benefited from an offensive line that has improved and a rising star wide receiver in Jaxon Smith‑Njigba, who leads the NFL in receiving yards (1,041). The chemistry between Darnold and Smith‑Njigba has become a major asset for Seattle’s offense.

Rams veteran Matthew Stafford has been in MVP conversations this season. He has 2,427 passing yards, 25 touchdowns, and just 2 interceptions in 9 games. He’s playing elite football, thriving in the Rams’ offensive scheme, and benefiting from key weapons such as Davante Adams and Puka Nacua.

Of course, one former Rams weapon is now a member of the Seahawks. Cooper Kupp won a Super Bowl MVP award as a member of the Rams. The Jake Paul lookalike is now a member of Seattle’s receiving corps and should receive a warm welcome from the crowd at SoFi Stadium.

Betting Trends

  • Both of these teams are 7-2 against the spread this season, tied for the best record in the league against the spread.
  • The over has cashed in six of Seattle’s first nine games.
  • The under has hit in five of the Rams’ first nine outings.
  • Stafford is 5‑0 against the Seahawks since joining the Rams in 2021.

Seahawks vs Rams Model Projection

  • Score Projection: Seattle Seahawks 24 – Los Angeles Rams 27
  • Win Probability: Los Angeles Rams 62% | Seattle Seahawks 38%

Final Thoughts

This is going to be a highly entertaining game between two prolific passing offenses in Inglewood. My best bet for this contest is the over, as Darnold and Stafford should continue dealing at the expense of the two defenses in this matchup.


Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: Los Angeles Rams, Seattle Seahawks
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