The Denver Broncos will host the Las Vegas Raiders on Thursday Night Football to kick off Week 10 of the NFL season. These teams are on opposite ends of the AFC West standings entering this game. Denver has the lead in this division and is on a hot streak. The Raiders are in last place and trying to end a losing streak. Before kickoff from the Mile High City, continue reading to get my Raiders vs Broncos prediction.
Our Raiders vs Broncos Pick
- Pick: Broncos -9.5
- Confidence: 3/5
Game Snapshot
- Matchup: Las Vegas Raiders vs Denver Broncos
- Date & Time: Thursday, November 6, 2025, 8:15 p.m. ET
- Venue: Empower Field at Mile High, Denver, Colorado
- Broadcast: Prime Video
Key Storylines
- The Broncos enter this game with a 7-2 record and have earned six straight victories. They’re playing at home in this game, where they are 4-0 on the season so far. The Broncos appear to be the team to beat in the AFC West and they will try to take advantage of another winnable game here to keep their lead over the Kansas City Chiefs.
- The Raiders are 2-6 and have had trouble putting together consistent performances. They are 1-3 on the road this year and turnovers have been a huge problem for them throughout the season.
- The Raiders played an overtime game last week, losing 30-29 to the Jacksonville Jaguars. Now they will need to regroup and play on a short week on the road against one of the hottest teams in football. That could be a recipe for disaster for Vegas.
- This game is a mismatch on paper. But it is still a division rivalry game and has the potential to go in any direction, thanks to the familiarity these teams have with one another.
Quarterback Play
Broncos signal-caller Bo Nix has been steady, efficient, and able to finish drives with touchdowns for his team. He has thrown for 1,976 yards, 17 touchdowns, and six interceptions on the season. Nix is also good at making plays with his legs when necessary.
Raiders starter Geno Smith has had his moments but has struggled with interceptions. His overall efficiency has been among the worst in the league among starting quarterbacks. Smith has 1,701 passing yards with 11 touchdowns and a league-high 11 interceptions. The Raiders need Smith to take better care of the football if they want any chance to win this game.
Betting Trends
- The Broncos are 4-4-1 against the spread going into Week 10.
- The Raiders are 3-5 against the spread through their first eight games.
- Denver has gone under the total in six of its first nine games.
- The Raiders are 3-5 on their totals so far this season.
Raiders vs Broncos Model Projection
Score Projection: Raiders 10 – Broncos 27
Win Probability: Raiders 25%, Broncos 75%
Final Thoughts
The Las Vegas Raiders are making too many mistakes to be a competitive football team in most games this season. They managed to lose respectably last week against a Jaguars team with an ill Trevor Lawrence at quarterback. But Geno Smith’s turnover woes make it hard to think that they will stay close on the road against the Broncos on a short week here. I’ll lay the points with Denver to kick off Week 10 in the NFL.
