Philadelphia 76ers vs Washington Wizards Prediction – 10/28/2025

The Philadelphia 76ers will hit the road to face the Washington Wizards on Tuesday night. This is the second game of a back-to-back for the Sixers, but they could have some key reinforcements back on the floor for this contest. Before the action begins, continue reading to get my 76ers vs Wizards prediction for Tuesday’s game.

Our 76ers vs Wizards Pick

• Pick: Philadelphia 76ers -5.5
• Confidence: 3/5

Game Snapshot

• Matchup: Philadelphia 76ers @ Washington Wizards
• Date & Time: Tuesday, October 28, 2025, 7:00 PM ET
• Venue: Capital One Arena, Washington, D.C.
• Broadcast: NBA League Pass

Key Storylines

• The 76ers are off to a fast start at 3–0 and have had huge contributions from Tyrese Maxey, who dropped 43 points in their latest win. He continues to be their offensive engine and will try to deliver for the second night in a row.
• The Sixers rested Joel Embiid for the front end of a back-to-back last night. His status is uncertain for this game, but he could play in this contest after being held out on Monday night. Jared McCain and Trendon Watford are sidelined for the Sixers.
• The Wizards are struggling early at 1–2 and have low expectations this season. Their defense appears to be one of the worst in the NBA early in the year and they will likely have their hands full with the explosive lineup of the Sixers.

Head-to-Head & Betting Trends

• The 76ers have scored an average of 126.0 points per game this season.
• The Wizards are scoring 116.7 points per game and are averaging 48 rebounds per game.
• Philadelphia is 2-1 against the spread going into this contest.
• The Wizards are 1-2 against the spread so far this season.
• The Sixers have gone over the total in all three of their games this year.
• Washington is 2-1 to the over through their first three games.

Best Player Props to Watch

76ers vs Wizards Model Projection

Score Projection: Philadelphia 76ers 123 – Washington Wizards 110
Win Probability: Philadelphia 76ers 62% , Washington Wizards 38%

Final Thoughts

The Sixers are my best bet for this contest from Washington. Embiid should play in this game and he should dominate against an undersized Wizards team that is missing one of its top frontcourt players in Bilal Coulibaly. I’ll lay the points with the Sixers here, as they should win for the second night in a row and keep their undefeated start to the season going.

Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.