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nc state vs notre dame prediction and preview

NC State vs Notre Dame Pick & Prediction – 10/11/2025

Updated October 10, 2025 • 3 min read

NC State and Notre Dame are set to face off at Notre Dame Stadium on Saturday afternoon. Notre Dame has won three games in a row after dropping their first two games of the season. They will try to get their fourth win in a row, this time against an NC State team that is two wins away from securing a bowl bid. Here, I break down this game and make my NC State vs Notre Dame prediction.

Our NC State vs Notre Dame Pick

  • Pick: NC State +22.5
  • Confidence: 3/5

Game Snapshot

  • Matchup: NC State Wolfpack vs Notre Dame Fighting Irish
  • Date & Time: Saturday, October 11, 2025, at 3:30 PM ET
  • Venue: Notre Dame Stadium, South Bend, IN
  • Broadcast: Peacock

NC State vs Notre Dame Odds

Betting MarketOdds
SpreadNotre Dame -22.5
MoneylineNotre Dame -2000, NC State +1000
Total Points59.5

Key Storylines

  • Notre Dame’s Offensive Firepower: Freshman quarterback CJ Carr has thrown for 766 yards and eight touchdowns during the team’s current three-game winning streak. The Irish boast one of the nation’s top-ranked offenses and they will try to keep their foot on the gas offensively this week.
  • NC State’s Road Challenges: The Wolfpack have struggled away from home, going 1-1 on the road during ACC play. They gave up 45 points to Duke in their last road game and will try to avoid getting torched in a similar fashion by Notre Dame.
  • Injuries Impacting Notre Dame: Wide receiver Jaden Greathouse and defensive back DeVonta Smith are confirmed out due to injury, affecting the Irish on both sides of the ball.

Quarterback Play

NC State: Quarterback CJ Bailey has been impressive, completing 74.6% of his passes for 1,660 yards, 13 touchdowns, and four interceptions. His ability to make explosive plays will be tested against a Notre Dame defense that is finding its rhythm after an 0-2 start.

Notre Dame: CJ Carr has displayed maturity beyond his years, leading the Irish offense with 1,280 passing yards and 11 touchdowns. He has running back Jeremiyah Love to help him, with Love entering this game with six touchdowns on the ground this season.

Betting Trends

  • Notre Dame: The Irish have won each of their last 22 games against ACC opponents at home.
  • NC State: The Wolfpack has failed to cover the spread in seven of its last eight games against non-conference opponents.
  • Over/Under: NC State is 4-2 to the over through its first six games of the season. Notre Dame is 4-1 to the over on the year.

NC State vs Notre Dame Model Projection

Score Projection: Notre Dame 40 – NC State 21

Win Probability: Notre Dame 85%, NC State 15%

Final Thoughts

Notre Dame should win this game pretty handily at home on Saturday afternoon. But I am going to take the points with NC State. The Irish have struggled on defense against respectable power conference opponents this year and CJ Bailey is certainly good enough at quarterback to help NC State keep this game within two or three possessions in South Bend.


Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: NC State Wolfpack, Notre Dame Fighting Irish
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