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New York Yankees vs Baltimore Orioles Pick - 4/30/2025

Baltimore Orioles vs New York Yankees Prediction – 9/27/2025

Updated September 27, 2025 • 3 min read

The Baltimore Orioles and New York Yankees will square off on Saturday afternoon at Yankee Stadium. The Yankees carry momentum after a resounding 8–4 win over Baltimore the night before, as the Yankees enter the day in a tie with the Toronto Blue Jays in the AL East standings. Before these division rivals battle in the Bronx, continue reading to get my Orioles vs Yankees prediction for Saturday’s game.

Our Orioles vs Yankees Pick

  • Pick: New York Yankees -1.5
  • Confidence: 4/5

Game Snapshot

  • Matchup: Baltimore Orioles vs New York Yankees
  • Date & Time: Saturday, September 27, 2025, 1:05 PM ET
  • Starting Pitchers: Tomoyuki Sugano (Orioles) vs Cam Schlittler (Yankees)
  • Stadium: Yankee Stadium, Bronx, NY
  • Broadcast: YES Network (Yankees), MASN (Orioles)

Key Storylines

Pitching matchup

Tomoyuki Sugano will get the start for the Orioles today. He enters this contest at 10-9 on the season and has a 4.54 ERA. Sugano has not generated many strikeouts this year. That has led to a lot of contact from opposing hitters and has been a big reason for his 30 home runs allowed on the year.

Cam Schlittler will take the hill for the Yankees in this important matchup for them. Schlittler is 3-3 on the season and has a very respectable 3.27 ERA. His strikeout rate is over one per inning and he is allowing under a hit per inning. The Yankees have a promising young arm in Schlittler to look forward to developing.

Recent team streaks

  • The Yankees have won six straight games and are in a tie with the Blue Jays for first place in the AL East.
  • Baltimore is 2-3 in its last five games and just wants to get to the finish line for the season.

Best Player Props

PlayerProp
Aaron JudgeOver 0.5 HR
Giancarlo StantonOver 0.5 HR
Gunnar HendersonOver 1.5 Total Bases

Betting Trends & H2H

  • The Yankees hold a 7-4 lead in their season series with Baltimore after winning Friday’s series opener.
  • With Friday’s win, the Yankees have clinched a victory in their season series with Baltimore.
  • The first game of this series went over its total, with 12 total runs scored.

Orioles vs Yankees Model Projection

Score Projection: Baltimore 3 – New York 5

Win Probability: Orioles 35%, Yankees 65%

Final Thoughts

I don’t see the Yankees having any problems getting the win in this game on Saturday afternoon. New York has something to play for at the end of the season and they have more than enough offensive talent to cover the runline. I’ll go with the Yankees to win this matchup by two runs or more, as they should keep the pressure on the Blue Jays to perform later in the day against the Tampa Bay Rays.


Jay Sanin

Jay Sanin is the GM and Head of Sports at ATS.io. He has been writing about sports gambling since 2013, handicapping tens of thousands of sporting events. He plays sides and totals aggressively across most sports and is more selective in player prop markets. He does his own modeling across most sports, and his family is jealous of how much time he spends on his precious spreadsheets.

Affiliate Disclosure ATS.io uses affiliate links. If you sign up through a link on this page, we may earn a commission at no additional cost to you. Rankings are based on hands-on testing and published criteria, and affiliate relationships do not determine placement.
Tags: Baltimore Orioles, New York Yankees
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